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Studies of the Guiyuan Fang and Autologous Bone Marrow Stem Cells Transplantation on Hepatic Injury and

Wu Limao,Li Lianda,Liu Hong,Ning Keyong,Li Yikui

Strategic Study of CAE 2004, Volume 6, Issue 7,   Pages 34-42

Abstract: The normal liver tissues showed very weak /xPA expression, and Guiyuan Fang caused a marked increaseThe fiPA expression in the autologous BMSCs transplantation group and Guiyuan Fang plus autologous BMSCs

Keywords： bone marrow stem cells     autologous transplantation     liver injury     liver fibrosis     guiyuan fang    

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Performance of completely autotrophic nitrogen removal over nitrite process under different aeration modes and dissolved oxygen

GUO Jinsong, YANG Guohong, FANG Fang, QIN Yu

Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 4,   Pages 439-445 doi: 10.1007/s11783-008-0046-4

Abstract: In this study, three sequential batch biofilm reactors (SBBRs) were operated for 155 days to evaluate the performance of completely autotrophic nitrogen removal over nitrite (CANON) process under different aeration modes and dissolved oxygen (DO). Synthetic wastewater with 160-mg NH-N/L was fed into the reactors. In the continuously-aerated reactor, the efficiency of the ammonium nitrogen conversion and total nitrogen (TN) removal reached 80% and 70%, respectively, with DO between 0.8–1.0 mg/L. Whereas in the intermittently-aerated reactor, at the aeration/non-aeration ratio of 1.0, ammonium was always under the detection limit and 86% of TN was removed with DO between 2.0–2.5 mg/L during the aeration time. Results show that CANON could be achieved in both continuous and intermittent aeration pattern. However, to achieve the same nitrogen removal efficiency, the DO needed in the intermittently-aerated sequential batch biofilm reactor (SBBR) during the aeration period was higher than that in the continuously-aerated SBBR. In addition, the DO in the CANON system should be adjusted to the aeration mode, and low DO was not a prerequisite to CANON process.

Keywords： Synthetic wastewater     process     Whereas     biofilm     detection    

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Boundedness of Marcinkiewicz integralwith rough kernel onTriebel-Lizorkin spaces

Chun-jie ZHANG,Fang-fang REN,Yu-huai ZHANG,Gui-lian GAO

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 8,   Pages 654-657 doi: 10.1631/FITEE.1500082

Abstract: This paper is a continuation of our previous work (Zhang and Chen, 2010b). Following the same general steps of the proof there, we make essential improvement on our previous theorem by recalculating a key inequality. Our result shows that the Marcinkiewicz integral, with a bounded radial function in its kernel, is still bounded on the Triebel-Lizorkin space.

Keywords： Marcinkiewicz integral     Triebel-Lizorkin spaces    

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Seasonal variation of nitrogen and phosphorus in Xiaojiang River—A tributary of the Three Gorges Reservoir

Zhe LI , Jinsong GUO , Man LONG , Fang FANG , Jinping SHENG , Hong ZHOU ,

Frontiers of Environmental Science & Engineering 2009, Volume 3, Issue 3,   Pages 334-340 doi: 10.1007/s11783-009-0039-y

Abstract: A yearlong monitoring program in the backwater area of Xiaojiang River (XBA) was launched in order to investigate the eutrophication of backwater areas in tributaries of the Yangtze River in the Three Gorges Reservoir (TGR) in China, starting after the impoundment water level of the TGR reached 156 m. From March 2007 to March 2008, the average concentration of total nitrogen (TN) and total phosphorus (TP) were (1553 ± 484) μg·L and (62 ± 31) μg·L, respectively. The mean value of chlorophyll was (9.07 ± 0.91) μg·L. The trophic level of XBA was meso-eutrophic, while the general nutrient limitation was phosphorus. The results indicated that XBA has a strong ability to purify itself and has non-point source pollution from terrestrial runoff. The variation of TN/TP ratio was caused by a variation in TN rather than in TP when TN/TP<22. N-fixation from cyanobacteria occurred and became an important process in overcoming the nitrogen deficit under a low TN/TP ratio. When TN/TP ≥ 22, the variation of TP affected the TN/TP ratio more significantly than TN. The increase of TP in XBA was caused mainly by particulate phosphorus, which could originate from a non-point source as adsorptive inorganic forms after heavy rainfall and surface runoff. An increase in the river’s flow could also contribute to an unstable environment for the growth of phytoplankton.

Keywords： Three Gorges Reservoir     eutrophication     nitrogen     phosphorus     seasonal variation     chlorophyll    

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Dimensional synthesis of a novel 5-DOF reconfigurable hybrid perfusion manipulator for large-scale spherical honeycomb perfusion

Hui YANG, Hairong FANG, Yuefa FANG, Xiangyun LI

Frontiers of Mechanical Engineering 2021, Volume 16, Issue 1,   Pages 46-60 doi: 10.1007/s11465-020-0606-2

Abstract: A novel hybrid perfusion manipulator (HPM) with five degrees of freedom (DOFs) is introduced by combining the 5PUS-PRPU (P, R, U and S represent prismatic, revolute, universal and spherical joint, respectively) parallel mechanism with the 5PRR reconfigurable base to enhance the perfusion efficiency of the large-scale spherical honeycomb thermal protection layer. This study mainly presents the dimensional synthesis of the proposed HPM. First, the inverse kinematics, including the analytic expression of the rotation angles of the U joint in the PUS limb, is obtained, and mobility analysis is conducted based on screw theory. The Jacobian matrix of 5PUS-PRPU is also determined with screw theory and used for the establishment of the objective function. Second, a global and comprehensive objective function (GCOF) is proposed to represent the Jacobian matrix’s condition number. With the genetic algorithm, dimensional synthesis is conducted by minimizing GCOF subject to the given variable constraints. The values of the designed variables corresponding to different configurations of the reconfigurable base are then obtained. Lastly, the optimal structure parameters of the proposed 5-DOF HPM are determined. Results show that the HPM with the optimized parameters has an enlarged orientation workspace, and the maximum angle of the reconfigurable base is decreased, which is conducive to improving the overall stiffness of HPM.

Keywords： 5-DOF hybrid manipulator     reconfigurable base     large workspace     dimensional synthesis     optimal design    

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Temperature variation of concrete box girder bridge

Jian WANG, Zhi FANG,

Frontiers of Structural and Civil Engineering 2009, Volume 3, Issue 4,   Pages 407-413 doi: 10.1007/s11709-009-0053-y

Abstract: On the basis of theoretical analysis and measurement on site, the temperature gradients and its variation on concrete box girder bridges resulting from ambient temperature, solar radiation, and structural temperature fields were discussed. With the help of the heat transfer theory and finite element method (FEM), the heat flux of the surface of concrete box girder was carried out, and all the heat fluxes were described as the convection. The results were compared with that from field measurements, and a good correlation was found. It was revealed that the methods, the parameters, the boundary condition used in this paper were reasonable. Last, some conclusions were obtained, which could provide the basis for box girder design under solar radiation.

Keywords： temperature     transfer     correlation     radiation     variation    

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Mutation profiling of 16 candidate genes in

Yang Zhang, Fang Wang, Xue Chen, Wenjing Liu, Jiancheng Fang, Mingyu Wang, Wen Teng, Panxiang Cao, Hongxing

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 229-237 doi: 10.1007/s11684-018-0616-1

Abstract: This retrospective analysis aimed to investigate the mutation profile of 16 common mutated genes in acute myeloid leukemia (AML) patients. A total of 259 patients who were diagnosed of AML were enrolled in this study. Mutation profiling of 16 candidate genes were performed in bone marrow samples by using Sanger sequencing. We identified at least 1 mutation in 199 of the 259 samples (76.8%), and 2 or more mutations in 31.7% of samples. was the most common mutated gene (16.2%, 42/259), followed by (15.1%, 39/259), (14.7%, 38/259), and (13.5%, 35/259). Concurrence was observed in 97.1% of the mutated cases and in 29.6% of the double mutated cases. Distinct patterns of co-occurrence were observed for different hotspot mutations within the gene: mutations were associated with and/or mutations, whereas mutations co-occurred with mutations only. Concurrence was also observed in 86.6% of epigenetic regulation genes, most of which co-occurred with mutations. The results showed certain rules in the mutation profiling and concurrence of AML patients, which was related to the function classification of genes. Defining the mutation spectrum and mutation pattern of AML will contribute to the comprehensive assessment of patients and identification of new therapeutic targets.

Keywords： leukemia     myeloid     acute     gene     mutation    

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Identification of Legionella species by the composition of cellular fatty acids

Cun-Lei FANG MD, Zhao-Hui HU PhD, Qing-Yi ZHU MD, Ya-Jun SONG PhD, Ya-Fang TAN PhD, Rui-Fu YANG PhD,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 208-215 doi: 10.1007/s11684-010-0031-8

Abstract: One hundred and fifty-three isolates from the environment and 36 reference strains of the were studied with regards to their composition of cellular fatty acids as determined by gas chromatography, and then were classified into 41 groups by numerical analysis. Most reference strains formed only a single group, except , , , , and , which were clustered into two or three groups. Even serological types of could be clearly identified. Therefore, in this study, numerical analysis of cellular fatty acid composition is an effective method for identifying species.

Keywords： Legionella     numerical analysis     identification     fatty acids composition    

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Effects of residual motion compensation errors on the performance of airborne along-track interferometric SAR Article

Hui ZHANG,Jun HONG,Xiao-lan QIU,Ji-chuan LI,Fang-fang LI,Feng MING

Frontiers of Information Technology & Electronic Engineering 2016, Volume 17, Issue 10,   Pages 1095-1106 doi: 10.1631/FITEE.1500311

Abstract: Two approximations, center-beam approximation and reference digital elevation model (DEM) approximation, are used in synthetic aperture radar (SAR) motion compensation procedures. They usually introduce residual motion compensation errors for airborne single-antenna SAR imaging and SAR interferometry. In this paper, we investigate the effects of residual uncompensated motion errors, which are caused by the above two approximations, on the performance of airborne along-track interferometric SAR (ATI-SAR). The residual uncompensated errors caused by center-beam approximation in the absence and in the presence of elevation errors are derived, respectively. Airborne simulation parameters are used to verify the correctness of the analysis and to show the impacts of residual uncompensated errors on the interferometric phase errors for ATI-SAR. It is shown that the interferometric phase errors caused by the center-beam approximation with an accurate DEM could be neglected, while the interferometric phase errors caused by the center-beam approximation with an inaccurate DEM cannot be neglected when the elevation errors exceed a threshold. This research provides theoretical bases for the error source analysis and signal processing of airborne ATI-SAR.

Keywords： Synthetic aperture radar (SAR)     Along-track interferometric     Motion compensation     Residual error     Interferometric phase    

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A metadata model for collaborative experiments and simulations in earthquake engineering

Jean-Pierre BARDET, Nazila MOKARRAM, Fang LIU

Frontiers of Structural and Civil Engineering 2010, Volume 4, Issue 2,   Pages 133-153 doi: 10.1007/s11709-010-0036-z

Abstract: Research projects in earthquake engineering yield a very large amount of complex data from experiments and computer simulations. Understanding and exchanging these complicated and voluminous data sets prompted the development of metadata models that document the processes of data generation, and facilitate the collaboration and exchange of information between researchers. The present metadata model was designed to document and exchange a large number of large data files in earthquake engineering, but is applicable to other fields of engineering and science. The model was conceived based on a series of former data models, which were unduly complicated and limited to few types of experiments. Simpler than its predecessors, the present metadata model applies to all kinds of earthquake engineering experiments. It was developed in the object-oriented framework using Protégé. Its applications are illustrated with examples from centrifuge experiments.

Keywords： metadata     data     documentation     experiment     simulation    

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Advances in structural mechanics of Chinese ancient architectures

YU Maohong, ODA Yoshiya, FANG Dongping, ZHAO Junhai

Frontiers of Structural and Civil Engineering 2008, Volume 2, Issue 1,   Pages 1-25 doi: 10.1007/s11709-008-0002-1

Abstract: Chinese ancient architectures are valuable heritage of ancient culture of China. Many historical building have been preserved up to now. The researches on the structural mechanics of ancient architectures show the different aspects of structure and mechanics. Systematical studies on the structural mechanics of ancient architectures have been carried out at Xi’an Jiaotong University since 1982. It is related with the need of repair of some national preservation relics in Xi’an. These studies include: 1) Ancient wooden structures including three national preservation relics Arrow Tower at North City Gate, City Tower at East City Gate, and Baogao Temple in Ningbao, Zhejiang province. 2) Ancient tall masonry building, the Big Goose Pagoda and Small Goose Pagoda in Xi’an. 3) Mechanical characteristics of ancient soil under foundation and city wall; the influence of caves in and under the ancient City Wall on the stability of the wall. 4) The typical Chinese ancient building at the center of city: the Bell Tower and Drum tower. 5) The behavior of Dou-Gong and Joggle joint of Chinese ancient wooden structure. 6) The mechanical behavior of ancient soils under complex stress state. A new systematical strength theory, the unified strength theory, is used to analyze the stability of ancient city wall in Xi’an and foundation of tall pagoda built in Tang dynasty. These researches also concern differential settlements of Arrow Tower and resistance to earthquake of these historical architecture heritages. Some other studies are also introduced. This paper gives a summary of these researches. Preservation and research are nowadays an essential requirement for the famous monuments, buildings, towers and others. Our society is more and more conscious of this necessity, which involves increasing activities of restoration, and then sometimes also of repair, mechanical strengthening and seismic retrofitting. Many historical buildings have in fact problems of structural strength and stability; the need for further studies on structural mechanics and materials is definitely growing.
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Zero increase in peak discharge for sustainable development

Xing Fang, Junqi Li, Yongwei Gong, Xiaoning Li

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 4, doi: 10.1007/s11783-017-0935-5

Abstract: For urban land development, some or all natural land uses (primarily pervious) are converted into impervious areas which lead to increases of runoff volume and peak discharge. Most of the developed countries require a zero increase in peak discharge for any land development, and the policy has been implemented for several decades. The policy of zero increase in peak discharge can be considered as historical and early stage for the low impact development (LID) and sustainable development, which is to maintain natural hydrological conditions by storing a part or all of additional runoff due to the development on site. The paper will discuss the policy, the policy implementation for individual projects and their impact on regional hydrology. The design rainfalls for sizing LID facilities that are determined in 206 weather stations in USA are smaller than design rainfalls for sizing detention basins. The zero-increase policy links to financial responsibility and sustainability for construction of urban stormwater infrastructures and for reducing urban flooding. The policy was compared with current practices of urban development in China to shine the light for solving urban stormwater problems. The connections and differences among LID practices, the zero-increase policy, and the flood control infrastructure were discussed. We promote and advocate the zero-increase policy on peak discharge for comprehensive stormwater management in China in addition to LID.

Keywords： Stormwater management     Detention basin     Zero increase     Peak discharge     Sustainable development     Design rainfall    

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A model of

Jingyu WANG,Hongwei FANG,Guojian HE,Lei HUANG

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 6,   Pages 845-853 doi: 10.1007/s11783-014-0708-3

Abstract: The impact on the environment of radionuclide release from nuclear power plants has attracted increased attention, especially after the accident at Fukushima Daiichi Nuclear Power Plant in Japan. Based on the mechanisms of adsorption/desorption at solid/liquid interfaces and a surface micromorphology model of sediments, a theoretical expression of the distribution coefficient is derived. This coefficient has significant effects on the distribution of radionuclide in seawater, suspended sediment and seabed sediment. is then used to simulate Sr transport in the sea near the Daya Bay Nuclear Power Plant. The simulation results are compared with field measurements of tidal level, current velocity, suspended sediment concentration and Sr concentrations in the same period. Overall, the simulated results agree well with the field measured data. Thus, the derived expression for is capable of interpreting realistic adsorption/desorption processes. What’s more, conclusion is drawn that about 40% Sr released by Daya Bay Nuclear Power Plant will be adsorbed by suspended sediment and 20% by seabed sediment, only about 40% Sr will remain in the sea near Daya Bay Nuclear Power Plant in South China Sea.

Keywords： distribution coefficient     Daya Bay     hydrodynamic     sediment transport     radionuclide transport    

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Design and analysis of Salisbury screens and Jaumann absorbers for solar radiation absorption

Xing FANG, C. Y. ZHAO, Hua BAO

Frontiers in Energy 2018, Volume 12, Issue 1,   Pages 158-168 doi: 10.1007/s11708-018-0542-6

Abstract: Two types of resonance absorbers, i.e., Salisbury screens and Jaumann absorbers are systematically investigated in solar radiation absorption. Salisbury screen is a metal-dielectric-metal structure which overcomes the drawback of bulky thickness for solar spectrum. Such structures have a good spectral selective absorption property, which is also insensitive to incident angles and polarizations. To further broaden absorption bandwidth, more metal and dielectric films are taken in the structure to form Jaumann absorbers. To design optimized structural parameters, the admittance matching equations have been derived in this paper to give good initial structures, which are valuable for the following optimization. Moreover, the analysis of admittance loci has been conducted to directly show the effect of each layer on the spectral absorptivity, and then the effect of thin films is well understood. Since the fabrication of these layered absorbers is much easier than that of other nanostructured absorbers, Salisbury screen and Jaumann absorbers have a great potential in large-area applications.

Keywords： thin films     admittance loci     solar absorber    

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Optically Digitalized Holography: A Perspective for All-Optical Machine Learning

Min Gu, Xinyuan Fang, Haoran Ren, Elena Goi

Engineering 2019, Volume 5, Issue 3,   Pages 363-365 doi: 10.1016/j.eng.2019.04.002

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Title Author Date Type Operation

Studies of the Guiyuan Fang and Autologous Bone Marrow Stem Cells Transplantation on Hepatic Injury and

Wu Limao,Li Lianda,Liu Hong,Ning Keyong,Li Yikui

Journal Article

Performance of completely autotrophic nitrogen removal over nitrite process under different aeration modes and dissolved oxygen

GUO Jinsong, YANG Guohong, FANG Fang, QIN Yu

Journal Article

Boundedness of Marcinkiewicz integralwith rough kernel onTriebel-Lizorkin spaces

Chun-jie ZHANG,Fang-fang REN,Yu-huai ZHANG,Gui-lian GAO

Journal Article

Seasonal variation of nitrogen and phosphorus in Xiaojiang River—A tributary of the Three Gorges Reservoir

Zhe LI , Jinsong GUO , Man LONG , Fang FANG , Jinping SHENG , Hong ZHOU ,

Journal Article

Dimensional synthesis of a novel 5-DOF reconfigurable hybrid perfusion manipulator for large-scale spherical honeycomb perfusion

Hui YANG, Hairong FANG, Yuefa FANG, Xiangyun LI

Journal Article

Temperature variation of concrete box girder bridge

Jian WANG, Zhi FANG,

Journal Article

Mutation profiling of 16 candidate genes in

Yang Zhang, Fang Wang, Xue Chen, Wenjing Liu, Jiancheng Fang, Mingyu Wang, Wen Teng, Panxiang Cao, Hongxing

Journal Article

Identification of Legionella species by the composition of cellular fatty acids

Cun-Lei FANG MD, Zhao-Hui HU PhD, Qing-Yi ZHU MD, Ya-Jun SONG PhD, Ya-Fang TAN PhD, Rui-Fu YANG PhD,

Journal Article

Effects of residual motion compensation errors on the performance of airborne along-track interferometric SAR

Hui ZHANG,Jun HONG,Xiao-lan QIU,Ji-chuan LI,Fang-fang LI,Feng MING

Journal Article

A metadata model for collaborative experiments and simulations in earthquake engineering

Jean-Pierre BARDET, Nazila MOKARRAM, Fang LIU

Journal Article

Advances in structural mechanics of Chinese ancient architectures

YU Maohong, ODA Yoshiya, FANG Dongping, ZHAO Junhai

Journal Article

Zero increase in peak discharge for sustainable development

Xing Fang, Junqi Li, Yongwei Gong, Xiaoning Li

Journal Article

A model of

Jingyu WANG,Hongwei FANG,Guojian HE,Lei HUANG

Journal Article

Design and analysis of Salisbury screens and Jaumann absorbers for solar radiation absorption

Xing FANG, C. Y. ZHAO, Hua BAO

Journal Article

Optically Digitalized Holography: A Perspective for All-Optical Machine Learning

Min Gu, Xinyuan Fang, Haoran Ren, Elena Goi

Journal Article